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What is Type 1 Diabetes?
[Borrowed from TEDDY web site]
Type 1 diabetes is one of the most common and serious long-term diseases in children. It is a disease where the body's immune system attacks the cells that make insulin. Insulin helps sugar (glucose) get into your cells so it can be used as energy. Children with type 1 diabetes must take insulin several times a day to stay alive and healthy. Right now, there is no cure for type 1 diabetes.
T1D is a serious disease affecting 1 out of every 300 (1/300) children in the United States. T1D occurs when special cells in the pancreas, called beta cells, are destroyed by the body's own immune system. When the beta cells are destroyed, the body can no longer make insulin.
Insulin is needed to keep blood sugar levels normal. If there is no insulin, your body can't use the sugars from the food you eat, causing serious illness or even death.
A child with T1D must take insulin shots or use an insulin pump every day to stay well. Insulin has to be taken every day for the rest of the life of a child with diabetes.
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What is  |
The aim of the Anti-Interleukin-1 in Diabetes Action trial (AIDA) study is to test the feasibility, safety/tolerability and potential efficacy of anti-IL-1 therapy in maintaining or enhancing beta-cell function in people with new-onset Type 1 diabetes. The study employs a randomized, placebo-controlled, double-masked, parallel-group, multi-centre design. Participating clinical centres are located in 11 countries throughout Europe. |
Supported by: The active drug (Kineret®) and the non active “dummy” drug are provided by Amgen. Amgen does not provide funding for the conduct of the trial or to the researchers. The expenses of the trial are funded by grants from Juvenile Diabetes Foundation International, New York, USA, the world’s largest private diabetes fund. Funding also provided by Oresund Diabetes Academy and Steno Diabetes Center, Denmark. |
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